Background：This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 （NRG3）. NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signaling through ERBB4.
仕様
Synonyms：HRG3,Neuregulin 3,Neuregulin 3 like polypeptide,Neuregulin-3,Neuregulin3,NRG-3,Nrg3,NRG3,Pro neuregulin 3,pro NRG3,Pro-NRG3
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human NRG3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：P56975
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
