Background：Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms：APG4 autophagy 4 homolog B,APG4B,ATG4 autophagy related 4 homolog B （S. cerevisiae）,ATG4B,ATG4B,AUT like 1 cysteine endopeptidase,AUT-like 1 cysteine endopeptidase,AUTL1,Autophagin 1,Autophagin-1,Autophagy related 4B cysteine peptidase,Autophagy related cysteine endopeptidase 1,Autophagy related protein 4 homolog B,Autophagy-related cysteine endopeptidase 1,Autophagy-related protein 4 homolog B,Cysteine protease ATG4B,hAPG4B,MGC1353
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human ATG4B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q9Y4P1
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
