Background：This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm. Poly（ADP-ribose） synthesized after DNA damage is only present transiently and is rapidly degraded by poly（ADP-ribose） glycohydrolase. Poly（ADP-ribose） metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-（ADP-ribose）, but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria.
仕様
Synonyms：[Protein ADP ribosylarginine] hydrolase like protein 2,[Protein ADP-ribosylarginine] hydrolase-like protein 2,ADP ribosylhydrolase 3,ADP ribosylhydrolase like 2,ADP-ribosylhydrolase 3,Adprhl2,AI836109,ARH3,ARHL2,ecto ADP ribosylhydrolase,FLJ20446,OTTMUSP00000009757,Poly（ADP ribose） glycohydrolase ARH3,Poly（ADP-ribose） glycohydrolase ARH3,Protein ADP ribosylarginine hydrolase like protein 2,RP23-113P22.3
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human ADPRHL2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
