Background：TRIAD1, also known as ARIH2 （ariadne homolog 2） or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor （CKR） gene cluster and a variety of human cancer-related gene loci.
仕様
Synonyms：HT005,all trans retinoic acid inducible RING finger,Ari 2,Ari-2,ARI2,ARI2,Ariadne 2,Ariadne 2 protein homolog,ariadne homolog 2 （Drosophila）,ariadne homolog 2,Ariadne RBR E3 ubiquitin protein ligase 2,ARIH 2,Arih2,E3 ubiquitin protein ligase ARIH2,E3 ubiquitin-protein ligase ARIH2,protein ariadne 2 homolog,Protein ariadne-2 homolog,Triad 1,TRIAD1,Triad1 protein,UIP48
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human ARIH2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：O95376
Isotype：IgG
Research Areas：Cell Biology, Epigenetics and Nuclear Signaling
