Background：The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein （APP）. It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Adapter protein X11beta,Amyloid beta A4 precursor protein-binding family A member 2,APBA2,APBA2,D15S1518E,HsT16821,LIN 10,MGC：14091,MGC99508,Mint 2,Mint-2,MINT2,Neuron-specific X11L protein,Neuronal Munc18-1-interacting protein 2,Phosphotyrosine binding/interacting domain （PTB） bearing protein,X11 beta,X11 like protein,X11l
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human APBA2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
