Background：This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
仕様
Synonyms：Activating enhancer binding protein 2 beta,Activating enhancer-binding protein 2-beta,AP 2B,AP2 B,AP2-beta,AP2B,AP2B,AP2beta,MGC21381,OTTHUMP00000039925,PDA2,TFAP 2B,Tfap2b,Transcription factor AP 2 beta,Transcription factor AP-2-beta,Transcription factor AP2 beta
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human TFAP2B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q92481
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
