Background：This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.
仕様
Synonyms：ACE 1,ACE,ACE T,ACE,ACE1,Angiotensin converting enzyme somatic isoform,Angiotensin converting enzyme testis specific isoform,Angiotensin I converting enzyme 1,Angiotensin I converting enzyme,Angiotensin I converting enzyme peptidyl dipeptidase A 1,angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript,Angiotensin-converting enzyme,Carboxycathepsin,CD 143,CD143,CD143 antigen,DCP 1,DCP,DCP1,Dipeptidyl carboxypeptidase 1,Dipeptidyl carboxypeptidase I,Kininase II,MGC26566,MVCD3,Peptidase P,Peptidyl dipeptidase A,soluble form,Testicular ECA
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human ACE
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：P12821
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction, Stem cells
