Background：This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD（+）-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid （GABA）. In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
仕様
Synonyms：Aldedehyde dehydrogenase 5 family,Aldehyde dehydrogenase 5 family member A1,Aldehyde dehydrogenase 5A1,Aldehyde dehydrogenase family 5 member A1,ALDH5A 1,Aldh5a1,mitochondrial,Mitochondrial succinate semialdehyde dehydrogenase,NAD（+） dependent succinic semialdehyde dehydrogenase,NAD（+）-dependent succinic semialdehyde dehydrogenase,SSADH,SSDH,SSDH,Succinate semialdehyde dehydrogenase,Succinate-semialdehyde dehydrogenase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human ALDH5A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P51649
Isotype：IgG
Research Areas：Cancer, Metabolism, Neuroscience, Signal transduction
