Background：This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid （RA） from retinaldehyde. Retinoic acid, the active derivative of vitamin A （retinol）, is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
仕様
Synonyms：AL1A2,Aldehyde dehydrogenase family 1 member A2,ALDH1A2 aldehyde dehydrogenase 1 family,member A2,ALDH1A2,Aldh1a7,AV116159,MGC26444,RALDH 2,RALDH（II）,Raldh1,RalDH2,RALDH2 T,Retinal dehydrogenase 2,Retinaldehyde dehydrogenase 2,Retinaldehyde specific dehydrogenase type 2,Retinaldehyde-specific dehydrogenase type 2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human ALDH1A2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：O94788
Isotype：IgG
Research Areas：Cancer, Developmental biology, Neuroscience
