Background：This gene encodes a member of the ADAM （a disintegrin and metalloprotease） protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.
仕様
Synonyms：A disintegrin and metalloproteinase domain 11,ADA11,ADAM 11,Adam11,and cysteine-rich protein,Disintegrin and metalloproteinase domain-containing protein 11,disintegrin-like,MDC,Metalloproteinase like,disintegrin like,and cysteine rich protein,Metalloproteinase-like
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human ADAM11
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：O75078
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
