Background:This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
仕様
Synonyms:9430099A16Rik,Long transient receptor potential channel 5,LTrpC-5,LTrpC5,MLSN1 and TRP related gene 1,MLSN1 and TRP related gene 1 protein,MLSN1 and TRP-related,MLSN1- and TRP-related gene 1 protein,MTR1,Novel protein similar to vertebrate transient receptor potential cation channel,subfamily M,member 5,Transient receptor potential cation channel subfamily M member 5,Transient receptor potential cation channel,subfamily M,member 5,Trpm5,TRPM5 transient receptor potential cation channel,subfamily M,member 5,TRPM5
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Synthetic peptide of human TRPM5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3