Background:The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
仕様
Synonyms:bZ1P14.9,FLJ11098,FLJ14863,FSGS2,MTRP6,Short transient receptor potential channel 6,si:rp71-1p14.9,Transient receptor potential cation channel subfamily C member 6,Transient receptor protein 6,TRP 6,TRP-6,TRP6,TRPC 6,Trpc6,TRPC6,TRRP6
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human TRPC6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3