Background：The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide （NO）, and thereby inhibits caspase-3 activity.
仕様
Synonyms：ADF,ATL derived factor,ATL-derived factor,DKFZp686B1993,MGC61975,SASP,Surface associated sulphydryl protein,Surface-associated sulphydryl protein,testicular tissue protein Li 199,THIO,Thioredoxin,thioredoxin delta 3,TRDX,TRX 1,Trx,TRX1,TXN,TXN delta 3,TXN protein,zgc：92903
Host：Rabbit
Reactivity：Human,Rat
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human TXN
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：1000-1：5000, IHC 1：50-1：200
Swissprot：P10599
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
