Background：The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome （LDAS）. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：AAT 5,AAT5,Activin A receptor type II like kinase 53kDa,Activin A receptor type II like kinase,53kD,Activin A receptor type II like protein kinase of 53kD,activin A receptor type II-like kinase,53kDa,activin A receptor type II-like protein kinase of 53kD,Activin receptor like kinase 5,Activin receptor-like kinase 5,ACVRLK 4,ACVRLK4,ALK 5,ALK-5,ALK5,LDS1A,LDS2A,MSSE,Serine/threonine protein kinase receptor R4,Serine/threonine-protein kinase receptor R4,SKR 4,SKR4,TbetaR I,TbetaR-I,TGF beta receptor type 1,TGF beta receptor type I,TGF beta type I receptor,TGF-beta receptor type I,TGF-beta receptor type-1,TGF-beta type I receptor,TGFBR 1,TGFBR1,TGFBR1 protein,TGFR 1,TGFR-1,TGFR1,TGFR1,Transforming growth factor beta receptor 1,Transforming growth factor beta receptor I （activin A receptor type II like kinase,53kD）,Transforming growth factor beta receptor I,transforming growth factor,beta receptor 1,transforming growth factor,beta receptor I （activin A receptor type II-like kinase,53kD）,Transforming growth factor-beta receptor type I
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human TGFBR1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P36897
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction, Stem cells
