Background：The protein involved in translocation of long-chain fatty acids （LFCA） across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids .Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.
仕様
Synonyms：ACSVL5,FATP 1,FATP,FATP1,Fatty acid transport protein 1,FLJ00336,Long chain fatty acid transport protein 1,MGC71751,SLC27A1,Solute carrier family 27 （fatty acid transporter） member 1,Solute carrier family 27 member 1
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.1mg/mL
Immunogen：Synthetic peptide of human SLC27A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q6PCB7
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
