Background：The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 （LQT3）, an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.
仕様
Synonyms：Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit,CDCD2,CMD1E,CMPD2,HB1,HB2,HBBD,HH1,ICCD,IVF,LQT3,PFHB1,Scn5a （gene name）,Scn5a,SCN5A,Sodium channel protein cardiac muscle alpha subunit,Sodium channel protein cardiac muscle subunit alpha,Sodium channel protein type 5 subunit alpha,Sodium channel protein type V alpha subunit,Sodium channel protein type V subunit alpha,SSS1,VF1,Voltage gated sodium channel alpha subunit Nav1.5,Voltage-gated sodium channel subunit alpha Nav1.5
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human SCN5A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：Q14524
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Neuroscience
