Background：The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II （CaMKII） pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.
仕様
Synonyms：GTP binding protein RAD,GTP-binding protein RAD,RAD,RAD,RAD1,RAS （RAD and GEM） like GTP binding 3,Ras associated with diabetes,Ras related associated with diabetes,REM3,RRAD
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human RRAD
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：P55042
Isotype：IgG
Research Areas：Cardiovascular, Signal transduction
