Background：Cyclic AMP-dependent protein kinase A （PKA） is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.
仕様
Synonyms：cAMP dependent protein kinase type I beta regulatory subunit,cAMP-dependent protein kinase type I-beta regulatory subunit,KAP1,PKARI beta,PRKAR 1,PRKAR 1B,PRKAR1,Prkar1b,PRKAR1B protein,Protein kinase cAMP dependent regulatory type I beta,RIbeta
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.9mg/mL
Immunogen：Synthetic peptide of human PRKAR1B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：1000-1：5000, IHC 1：50-1：200
Swissprot：P31321
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
