Background：The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid （glutarate, ketoglutarate, etc）. Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid （DMPS） By similarity.
仕様
Synonyms：FLJ55736,hOAT1,hPAHT,hROAT1,MGC45260,OAT1,Organic anion transporter 1,OTTHUMP00000236796,OTTHUMP00000236797,OTTHUMP00000236798,OTTHUMP00000236799,PAH transporter,PAHT,Para aminohippurate transporter,Renal organic anion transporter 1,ROAT1,S22A6,SLC22A6,Solute carrier family 22 （organic anion transporter） member 6,Solute carrier family 22 member 6
Host：Rabbit
Reactivity：Human,Rat
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human SLC22A6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：Q4U2R8
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
