Background：This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B （NFkB）. The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.
仕様
Synonyms：CVID10,DNA binding factor KBF2,H2TF1,Lymphocyte translocation chromosome 10 protein,LYT 10,NF kB2,NFKB p52/p100 subunit,Nuclear factor Kappa B subunit 2,Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 （p49/p100）,Nuclear factor of kappa light polypeptide gene enhancer in B cells 2,Oncogene Lyt 10,p100,Transcription factor NFKB2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human NFKB2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：1000-1：5000
Swissprot：Q00653
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
