Background:This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
仕様
Synonyms:AI607462,cytoplasmic 2,KIAA0611,NF ATc2,NF ATp,NF-ATc2,NF-ATp,NFAC2,NFAT 1,NFAT pre existing subunit,NFAT pre-existing subunit,NFAT transcription complex,preexisting component,NFAT1,NFAT1-D,NFATc2,NFATp,Nuclear factor of activated T cells cytoplasmic 2,Nuclear factor of activated T cells cytoplasmic calcineurin dependent 2,Nuclear factor of activated T cells pre-existing component,Nuclear factor of activated T cells,preexisting component,Nuclear factor of activated T-cells,Preexisting nuclear factor of activated T cells 2,T cell transcription factor NFAT 1,T-cell transcription factor NFAT1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.7mg/mL
Immunogen:Synthetic peptide of human NFATC2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:Q13469
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Immunology, Signal transduction