Background:This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.
仕様
Synonyms:AF6,AFAD,Afadin,ALL1-fused gene from chromosome 6 protein,Mllt4,Protein Af-6,Protein AF6
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.2mg/mL
Immunogen:Synthetic peptide of human MLLT4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:P55196
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction