Background:This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.
仕様
Synonyms:AGAP 1,AGAP-1,Agap1,AGAP1,Arf GAP with GTP binding proteinlike ANK repeat and PH domains 1,Arf-GAP with GTPase,ANK repeat and PH domain-containing protein 1,ArfGAP with GTPase domain ankyrin repeat and PH domain 1,Centaurin gamma 2,Centaurin-gamma-2,CENTG2,Cnt-g2,GGAP 1,GGAP1,GTP binding and GTPase activating protein 1,GTP-binding and GTPase-activating protein 1,KIAA1099,MGC71657
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Synthetic peptide of human AGAP1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3