Background:The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
仕様
Synonyms:cytoplasmic 4,NF ATc4,NF-AT3,NF-ATc4,NFAC4,NFAT3,NFATc4,Nuclear factor of activated T cells cytoplasmic 4,Nuclear factor of activated T cells cytoplasmic calcineurin dependent 4,Nuclear factor of activated T-cells,T cell transcription factor NFAT3,T-cell transcription factor NFAT3
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Synthetic peptide of human NFATC4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:Q14934
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction