Background：The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
仕様
Synonyms：Bpb,NEF,Protein S100-A1,S-100 protein alpha chain,S-100 protein subunit alpha,S100 alpha,S100 beta,S100 calcium binding protein A1,S100 calcium binding protein B,S100 calcium-binding protein A1,S100 protein alpha polypeptide,S100A,s100a1,S100B,S100beta,S10A1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human S100A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：100
Swissprot：P23297
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction, Tags ＆ Cell Markers
