Background：The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
仕様
Synonyms：ATP receptor,P2 purinoceptor subtype Y1,P2RY1,P2RY1,P2Y purinoceptor 1,P2Y1,P2Y1 purinoceptor,Platelet ADP receptor,Purinergic receptor,Purinergic receptor P2Y G protein coupled 1,Purinergic receptor P2Y1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human P2RY1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：P47900
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
