Background：The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.
仕様
Synonyms：Cell growth-inhibiting gene 29 protein,GIG29,Growth inhibiting protein 29,Na / bile acid cotransporter,Na / taurocholate transport protein,Na（+）/bile acid cotransporter,Na（+）/taurocholate transport protein,Na/taurocholate cotransporting polypeptide,NTCP,NTCP,NTCP1,SLC10A1,Sodium/bile acid cotransporter,Sodium/taurocholate cotransporter polypeptide,hepatic,Sodium/taurocholate cotransporting polypeptide,Solute carrier family 10 （sodium/bile acid cotransporter family） member 1,Solute carrier family 10 member 1
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human SLC10A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：15-1：50
Swissprot：Q14973
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
