Background：This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99％ identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
仕様
Synonyms：14 3 3 protein T cell,14 3 3 protein tau,14 3 3 protein theta,14 3 3 tau,14 3 3 theta,14-3-3 protein T-cell,14-3-3 protein tau,14-3-3 protein theta,1433T,1C5,HS1,KCIP1,Protein HS1,Protein kinase C inhibitor protein 1,Protein tau,tyr3/trp5 monooxygenase activation protein,theta,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,theta polypeptide,Ywhaq
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human YWHAQ
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：1000-1：5000, IHC 1：25-1：100
Swissprot：P27348
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction, Stem cells
