Background:Leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3) was identified by microarray analysis among genes that show differential expression during gastrulation in Xenopus laevis.Lrig3was expressed in the neural plate and neural crest (NC) at neurula stages, and in NC derivatives and other dorsal structures during tailbud stages. A prominent consequence of the morpholino-induced inhibition ofLrig3expression was impaired NC formation, as revealed by the suppression of marker genes, including Slug, Sox9 and Foxd3.
仕様
Synonyms:Leucine-rich repeats and immunoglobulin-like domains protein 3,Leucine-rich repeats- and immunoglobulin-like domains- containing protein 3,LIG-3,LIG3,LRIG1-3,Lrig3,LRIG3
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:1.2mg/mL
Immunogen:Synthetic peptide of human LRIG3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:Q6UXM1
Isotype:IgG
Research Areas:Cancer, Developmental biology, Neuroscience, Stem cells