Background：This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments （S1-S6）, and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif （GYGD）. The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia （AEMK）.
仕様
Synonyms：AEMK,EA1,Episodic ataxia with myokymia,HBK1,HUK1,Kca1 1,Kcna1,KCNA1,Kcpvd,KV1.1,MBK1,mceph,MGC124402,MGC126782,MGC138385,MK1,MK1,mouse,homolog of KV1.1,Potassium channel protein 1,Potassium voltage gated channel shaker related subfamily member 1,Potassium voltage gated channel subfamily A member 1,Potassium voltage gated channel,shaker related subfamily,member 1 （episodic ataxia with myokymia）,Potassium voltage-gated channel subfamily A member 1,RBK1,RCK1,Shak,Shaker related subfamily member 1,Voltage gated potassium channel subunit Kv1.1,Voltage-gated K（+） channel HuKI,Voltage-gated potassium channel HBK1,Voltage-gated potassium channel subunit Kv1.1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human KCNA1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
