Background：Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
仕様
Synonyms：HK5,Kallikrein 5,Kallikrein L2,Kallikrein like 2,Kallikrein like protein 2,Kallikrein related peptidase 5,Kallikrein-5,Kallikrein-like protein 2,Kallikrein5,KLK 5,KLK L2,KLK-L2,KLK5,KLK5,KLKL 2,KLKL2,SCTE,Stratum corneum tryptic enzyme,UNQ570/PRO1132
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Synthetic peptide of human KLK5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：1000-1：5000, IHC 1：100-1：300
Swissprot：Q9Y337
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
