Background：RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.
仕様
Synonyms：IASPP,inhibitor of apoptosis stimulating protein of p53,Inhibitor of ASPP protein,NFkB interacting protein 1,NKIP1,PPP1R13B-like protein,PPP1R13L,Protein iASPP,protein phosphatase 1 regulatory （inhibitor） subunit 13 like,RAI,RelA-associated inhibitor
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Synthetic peptide of human PPP1R13L
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：25-1：100
Swissprot：Q8WUF5
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
