Background：At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.
仕様
Synonyms：CBX 3,CBX3,CBX3,Chromobox homolog 3 （HP1 gamma homolog,Drosophila）,Chromobox homolog 3,Chromobox protein homolog 3,GAMMA,HECH,Heterochromatin like protein 1,Heterochromatin protein 1 homolog gamma,Heterochromatin protein HP1 gamma,HP1 gamma,HP1 gamma homolog,HP1Hs gamma,Modifier 2 protein
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human CBX3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：Q13185
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
