Background：This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go （eag） gene. Mutations in this gene can cause long QT syndrome type 2 （LQT2）. Transcript variants encoding distinct isoforms have been identified. Pore-forming （alpha） subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart （IKr）. Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.
仕様
Synonyms：eag homolog,Eag-related protein 1,ERG,ERG-1,ERG1,Ether a go go related potassium channel protein,Ether-a-go-go-related gene potassium channel 1,Ether-a-go-go-related protein 1,H ERG,H-ERG,HERG 1,HERG,hERG-1,hERG1,KCNH2,KCNH2,Kv11.1,LQT 2,LQT2,Potassium channel HERG,Potassium voltage gated channel subfamily H （eag related） member 2,Potassium voltage-gated channel subfamily H member 2,SQT1,Voltage gated potassium channel,subfamily H,member 2,Voltage-gated potassium channel subunit Kv11.1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human KCNH2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q12809
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Neuroscience
