Background:This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).
仕様
Synonyms:RK,RHOK,GPRK1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Synthetic peptide of human GRK1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:Q15835
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction