Background:GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.
仕様
Synonyms:GDNF family receptor alpha 3,GDNF family receptor alpha-3,GDNF receptor alpha-3,GDNFR-alpha-3,GDNFR3,GFR-alpha-3,GFRA3,GFRA3,Glial cell line derived neurotrophic factor receptor alpha 3,GPI linked receptor,OTTHUMP00000159486,OTTHUMP00000224020
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.8mg/mL
Immunogen:Synthetic peptide of human GFRA3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3