Background:Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
仕様
Synonyms:Basement membrane protein 90,BM 90,FBLN,Fbln1,FBLN1,FIBL 1,FIBL-1,FIBL1,Fibulin 1,Fibulin-1
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Synthetic peptide of human FBLN1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:100-1:300
Swissprot:P23142
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Signal transduction