Background：Ectonucleotide pyrophosphatase/phosphodiesterase family member 7（E-NPP 7） also known asalkaline sphingomyelin phosphodiesterase（Alk-SMase） orintestinal alkaline sphingomyelinaseis anenzymethat in humans is encoded by theENPP7gene. Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Not inhibited by ADP, AMP and EDTA. Detected in the colon （at protein level）. Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.
仕様
Synonyms：ALK SMase,Alk-SMase,Alkaline sphingomyelin phosphodiesterase,E-NPP 7,Ectonucleotide pyrophosphatase/phosphodiesterase 7,Ectonucleotide pyrophosphatase/phosphodiesterase family member 7,ENPP7,ENPP7,Intestinal alkaline sphingomyelinase,NPP-7
Host：Rabbit
Reactivity：Human,Rat
Applications：WB,IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human ENPP7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：Q6UWV6
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
