Background：The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides： ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：ABCDS,Ednra,EDNRB,EDNRB,Endothelin B receptor,Endothelin B receptor precursor,Endothelin receptor Non selective type,Endothelin receptor non-selective type,Endothelin receptor type B,ET B,ET-B,ET-BR,ETB,ETBR,ETRB,Hirschsprung disease 2,HSCR,HSCR2,OTTHUMP00000018534,OTTHUMP00000178736,WS4A
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human EDNRB
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
