Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
仕様
Synonyms:TNFRSF 21,BM 018,BM018,CD358,Death receptor 6,DR 6,DR6,MGC31965,OTTHUMP00000039915,TNFR related death receptor 6,TNFRSF21,TNFRSF21 protein,TNR21,Tumor necrosis factor receptor superfamily member 21,Tumor necrosis factor receptor superfamily member 21 precursor
Host:Rabbit
Reactivity:Human
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Synthetic peptide of human TNFRSF21
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3