Background:This gene encodes a protein with multiple coiled coil motifs which is located in the Nucleus, Cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms:C1orf136,DISC1,DISC1,Disrupted in schizophrenia 1,Disrupted in schizophrenia 1 protein,KIAA0457,RP4-730B13.1,SCZD9
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Synthetic peptide of human DISC1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3