Background：Collapsin response mediator protein 1, encoded by theCRMP1gene, is a humanproteinof theCRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.
仕様
Synonyms：Collapsin response mediator protein 1,CRMP 1,CRMP-1,Crmp1,Dihydropyrimidinase like 1,Dihydropyrimidinase related protein 1,Dihydropyrimidinase-related protein 1,DPYL1,DPYSL1,DRP 1,DRP-1,DRP1,ULIP-3,Ulip3,Unc-33-like phosphoprotein 3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human CRMP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：1000
Swissprot：Q14194
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
