Background：This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms：Collapsin response mediator protein 2,Collapsin response mediator protein,Collapsin response mediator protein hCRMP 2,CRAM,CRMP 2,CRMP-2,CRMP2,DHPRP 2,DHPRP2,Dihydropyrimidinase 2,Dihydropyrimidinase like 2,Dihydropyrimidinase like 2 long form,Dihydropyrimidinase related protein 2,Dihydropyrimidinase-related protein 2,DPYL 2,DPYL2,DPYL2,DPYSL 2,Dpysl2,DRP-2,DRP2,Musunc 33,Musunc33,N2A3,TOAD 64,TOAD64,ULIP 2 protein,ULIP-2,Ulip2,Unc-33-like phosphoprotein 2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human DPYSL2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
