Background：The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
仕様
Synonyms：Cdc 18L,Cdc 6,CDC18 （cell division cycle 18,S.pombe,homolog） like,CDC18 （S.pombe）,Cdc18 related protein,CDC18（S.pombe）,Cdc18-related protein,Cdc18L,cdc6,CDC6 cell division cycle 6 homolog,CDC6 related protein,CDC6-related protein,CDC6,Cdc6p,CELL CYCLE CONTROLLER CDC6,Cell division control protein 6,Cell division control protein 6 homolog,Cell division cycle 6 homolog （S. cerevisiae）,Cell division cycle 6 homolog,Cell division cycle 6,S. cerevisiae,homolog of,HsCDC 6,HsCDC18,HsCDC6,p62,p62（cdc 6）,p62（cdc6）
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human CDC6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q99741
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
