Background：The protein plays a central role in regulation of apoptosis via its interaction with p53/TP53.Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.It contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins.
仕様
Synonyms：Apoptosis-stimulating of p53 protein 1,ASPP1,p53BP2 like,p85,Ppp1r13b,Protein phosphatase 1 regulatory subunit 13B
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human ASPP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
