Background：This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta （TGF-beta） superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：Activin A receptor type 1B,Activin A receptor type II like kinase 4,Activin A type 1B receptor,Activin A type IB receptor,Activin receptor like kinase 4,Activin receptor type 1B,Activin receptor type IB,Activin receptor type-1B,Activin receptor-like kinase 4,ACTR IB,ACTR-IB,ACTRIB,ACV1B,ACVR 1B,Acvr1b,ACVRLK 4,ACVRLK4,ALK 4,ALK-4,ALK4,Serine（threonine） protein kinase receptor R2,Serine/threonine-protein kinase receptor R2,SKR 2,SKR2
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human ACVR1B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：P36896
Isotype：IgG
Research Areas：Cancer, Signal transduction, Stem cells
