Background：This gene encodes a member of the ADAMTS （a disintegrin and metalloproteinase with thrombospondin motifs） protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 （TS） motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.
仕様
Synonyms：A disintegrin and metalloproteinase with thrombospondin motifs 11,A disintegrin and metalloproteinase with thrombospondin motifs 5,A disintegrin like and metalloprotease （reprolysin type） with thrombospondin type 1 motif 5,A disintegrin like and metalloprotease （reprolysin type） with thrombospondin type 1 motif,5 （aggrecanase 2）,A disintegrin-like and metalloprotease with thrombospondin type 1 motif,5,A Disintigrin And Metalloproteinase with ThromboSpondin motif-5,ADAM metallopeptidase with thrombospondin type 1 motif 5,ADAM TS 11,ADAM TS 5,ADAM TS5,ADAM-TS 11,ADAM-TS 5,ADAM-TS5,ADAMTS 11,ADAMTS 5,ADAMTS-11,ADAMTS-5,ADAMTS11,ADAMTS11,formerly,Adamts5,ADMP 2,ADMP-2,ADMP2,Aggrecanase 2,Aggrecanase-2,ATS5,FLJ36738,Implantin,ThromboSpondin motif-5
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human ADAMTS5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：Q9UNA0
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
