Background:Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5 gene.It is sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc.It involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in brain.
仕様
Synonyms:4F2 LC,4F2 light chain,4F2LC,CD98,CD98 light chain,CD98LC,D16S469E,DC49,E16,hLAT1,Integral membrane protein E16,L type amino acid transporter,L type amino acid transporter 1,L-type amino acid transporter 1,Large neutral amino acids transporter 1,Large neutral amino acids transporter,Large neutral amino acids transporter small subunit 1,LAT1,LAT1,Membrane protein E16,MPE16,Slc7a5,Sodium independent neutral amino acid transporter,Sodium independent neutral amino acid transporter LAT1,Solute carrier family 7 (cationic amino acid transporter y+ system) member 5,Solute carrier family 7 member 5,TA1,Tumor associated protein 1,y+ system cationic amino acid transporter
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human SLC7A5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:Q01650
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction