Background：The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
仕様
Synonyms：ACE 2,ACE related carboxypeptidase,ACE-related carboxypeptidase,ACE2,ACE2,ACEH,Angiotensin converting enzyme 2,Angiotensin converting enzyme homolog,Angiotensin converting enzyme like protein,Angiotensin I Converting Enzyme （peptidyl dipeptidase A） 2,Angiotensin I converting enzyme 2,Angiotensin-converting enzyme homolog,DKFZP434A014,EC 3.4.17,metalloprotease MPROT 15,Metalloprotease MPROT15,OTTHUMP00000022963,Processed angiotensin-converting enzyme 2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human ACE2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：100-1：300
Swissprot：Q9BYF1
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular
