Background：This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
仕様
Synonyms：ARM10,Armadillo repeat containing 10,Armadillo repeat containing protein 10,Armadillo repeat-containing protein 10,ARMC 10,ARMC10,FLJ37850,MGC3195,PNAS112,Specific splicing variant involved in hepatocarcinogenesis,Splicing variant involved in hepatocarcinogenesis protein,SVH
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human ARMC10
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：20-1：100
Swissprot：Q8N2F6
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
